New photobiomodulation device for prevention and cure of radiotherapy‑induced oral mucositis and dermatitis: results of the prospective Safe PBM study
Safe PBM is a French, multicentric, prospective, non-comparative study which include patients with head and neck cancer or breast cancer treated in prophylactic or curative setting.
CareMin650 is feasible, safe, and well tolerated for preventive or curative treatment of OM and RD in cancer patients treated with RT.
Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines.
PBM is recommended for the prevention of OM & related pain in cancer patients treated with hematopoietic stem cell transplantation, H&N radiotherapy and H&N radiotherapy with chemotherapy.
Low level laser therapy against radiation induced oral mucositis in elderly head and neck cancer patients-a randomized placebo controlled trial.
LLLT decreases severity of OM and oral pain
Lesser weight loss, less morphine analgesic use and less radiation break in LLLT group
A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis.
Consistent evidence that red & infrered LLLT can partly prevent development of cancer therapy-induced OM
LLLT reduces significantly pain, severity & duration of symptoms in patients with cancer therapy-induced OM
Limitation of laser therapy due to heterogeneous laser parameters